IISA-2020 is the eleventh conference in the IISA series, technically co-sponsored by IEEE (approval pending), the University of Piraeus and the University of Thessaly. IISA-2020 Proceedings will be published in IEEE Explore (approval pending). The conference is intended to become an international forum for researchers and professionals in all areas of Information, Intelligence, Systems and Applications. We invite submissions of papers presenting high-quality original research and developments for the conference tracks listed below. The conference will last for three days and will feature tutorials, technical paper presentations, workshops, and distinguished keynote speeches. In IISA-2020, the Biological & Artificial Intelligence Foundation will give best student-paper awards.